PROFESSOR PEI-GEN XIAO
Professor XIAO Pei-gen is the founder and academic leader of Chinese medicinal plant as well as Chinese Materia Medica (CMM), and also a world-renowned ethnopharmacologist. He graduated in 1953 from Amoy University majoring in Biology. After graduation, he served at the Institute of Materia Medica, Chinese Academy of Medical Sciences (CAMS). Since 1983 he has been a professor and was designated as the director of Institute of Medicinal Plant Development (IMPLAD), CAMS. Starting from 1996 he has been designated as honorary director of IMPLAD, CAMS, and head of
Key Laboratory on Resource Utilization and Conservation of Chinese Materia Medica, State Administration of Traditional Chinese Medicine.
        During his long period of research professor, Prof. XIAO is good at the integration of traditional experience and modern scientific knowledge on CMM as well as ethnopharmacology, and has made great contribution in this field home and abroad.
He initiated the establishment of systematic investigation and studies on resources of CMM. In the early 1950s, he organized and conducted nationwide survey on CMM, his footmarks covered nearly the whole China. During the survey, Prof. XIAO had thoroughly investigated the original plants of CMM, and thereby found 1 new genus, 32 new species and 11 new varieties, including Fritillaria unibracteata, Coptis deltoidea and Astragalus membranaceus var. mongholicus.
        He has published more than 500 scientific papers and twenty scientific books. He is currently making great efforts in the hope of establishing a new discipline “Phytomedicophylogeny” (药用植物亲缘学).
        Due to his outstanding scientific achievements, he has been elected as member (academician) of Chinese Academy of Engineering, Division of Medicine and Health Engineering since 1994 and was also elected as president of the International Society on Ethnopharmacology in 1994.

PROFESSOR SHI-LIN CHEN
Prof. Shi-Lin Chen is the director of Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences & Peking Union Medical College and the director of the WHO Center for Collaboration on Traditional Medicine. Besides, he is working as the director of Engineering Research Center of Chinese Traditional Medicine Resources, Ministry of Education. Prof. Chen obtained his Ph.D from Chengdu University of Traditional Chinese Medicine and he has been the Visiting Professor in Hong Kong Polytechnic
University. Having been trained in Royal Botanic Garden, Kews, Prof. Chen is concurrently acting as the secretary of the GAP Association of Chinese Medicinal Material. He holds a concurrent position as the editor of such reputed Chinese medicinal research journals as China Journal of Chinese Materia Medica, Chinese medicines, Journal of Chinese Pharmaceutical Science, Chinese Traditional and Herbal Drugs, World Sciences and Technology etc. He has so far published more than 160 scientific papers and a few books. Research interests: Research on technology of the development and utilization of medicinal plant resources.

PROFESSOR Xiao-Bo SUN
Dr. Xiao-bo SUN is currently the deputy director of Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College (PUMC). As a national outstanding scientist and Ph.D. Supervisor in TCM University of Heilongjiang, Dr. SUN was a warded with the Government's Special Subsidy granted by the State Council. He has acted as the expert for evaluation of the national-level new drugs, basic drugs, progress in S&T, and national science foundation,. Dr. Chen holds a concurrent position as the editor of such reputed Chinese medicinal
research journals as China Journal of Chinese Materia Medica, Chinese Traditional and Herbal Drugs, World Sciences and Technology, etc.. Awarded with the Innovation Prize in S&T, Dr. SUN has obtained the special fund from Ministry of Personnel and besides, has been elected as one of Ten Outstanding Young People in Jilin Province .
Dr. SUN has been involved in more than seventy projects and received national and provincial awards for his scientific outcomes. Funded with forty national level and provincial projects, his research into LongYa Guanxin Capsule has been funded six million RMB Yuan by National Development and Reform Commission as the special fund to invigorate Industrial Base in northeast China.
Dr. SUN has published over 100 academic papers, including ten SCI papers. He edited 2 monographs, co-edited 7 monographs, and took charge of about 30 projects on R&D of new drugs which produced values for nearly one billion RMB yuan.
Dr. SUN is actively involved in international exchange and cooperation, having a good understanding of tendency in S&T home and abroad. He has once studied in Japan and made joint research in Singapore , USA , Thailand and South Korea .

PROFESSOR Jian-he WEI
Dr. Jian-he Wei is currently the deputy director of Institute of Medicinal Plant Development (IMPLAD) of Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College (PUMC), and the director of IMPLAD Hainan Branch, and Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine. He is also the head of Genetic Resources and Molecular Breeding Laboratory (GRAMBL) and the National Medicinal Plant Gene Bank (NMPGB). He was supported by the New Star Program of Beijing Science and Technology and the Program
for New Century Excellent Talents in University (NCET).
        Dr. Wei focuses his studies in medicinal plant breeding, molecular regulation of herb quality, GAP and genetic resources. He has published about 90 papers and five books. Dr. Wei has been granted two National Prize and three Provincial or Ministry Prize for Progress in Science and Technology. He has visited and got training in Philippines, France, and Switzerland.

PROFESSOR Shun-xing GUO
Doctor, professor, doctoral supervisor, director of Biotechnology Centre, director of "Three-level Laboratory of State Administration of Traditional Chinese Medicine Resource Conservation ", deputy director of the "Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education of PRC", degree evaluation committee and academic committee member of Beijing Union Medical College & Chinese Academy of Medical Sciences”, degree evaluation committee chairman, vice director of academic committee of Institute of Medicinal
Plant Development, review expert of National Drug Research, Functional Food and New Resources Food, editorial board member of “Chinese Pharmaceutical Journal” and “China Journal of Chinese Materia Medica”.
        He received 10 items of National Natural Science Funds, including one National Outstanding Youth Science Foundation, one Key Project and eight other Projects, published 240 research papers in domestic and foreign academic journals, received 7 provincial-level scientific and technological progress achievement award and 1 national grade II prize of science and authorized 10 national invention patents, supervised 16 postgraduate students, 45 doctor students and 6 postdoctoral.
        He has received many honors, such as “Special Government Allowance”, “Young Stars of the National Medical Technology”, “National Excellent Doctoral Dissertation of the first 100 ”, “Advanced Individual of Beijing Health Systems”, “Outstanding Mid-Aged Expert of the Ministry of Public Health”, “National Science Fund for Distinguished Young Scholars”. He is also the candidate of “the New Century National Hundred, Thousand and Ten Thousand Talent Project”.
        Major research direction:mycorrhizal biology research for Rare and endangered medicinal plants

PROFESSOR Xin-min LIU
Dr. Xin-min Liu, Prof.& Director in the Research center for Pharmacology and Toxicology
        Prof. Dr. Liu got his Ph. D from Peking Union Medical College in 1996; He is currently the member of Expert Advisory Panel on Traditional Medicine, World Health Organization, the Deputy Secretary-General of Professional Committee of Chinese Material Medica, World Federation of Chinese Medicine Society, as well as the editors and reviewers for several domestic and international academic journals. Prof. Dr. Liu is being actively engaged in the field of
Neuropharmacology and Neoplastic Pharmacology research on medicinal plants, development of methodology for Behavioral Neuropharmacology, as well as innovative strategy research for TCM modernization and globalization. He has been funded more than 20 projects from the National Natural Science Foundation, the Ministry of Science and Technology(MOST) and the Satate Administration of Traditional Chinese Medicine of China(SATCM), as well as the EU- FP7 (Seventh Framework Programme ).
        Prof. Dr. Liu has been in collaboration with Chinese Astronaut Centre , and Sion-bioway Group and developed a proprietary, automated, large-scale data acquisition and good laboratory practice compliance computer real-time image analyzing systems and comprehensive evaluation scales for animal behavior studies (memory enhancement , improve depression / anxiety and sleep, anti-fatigue) .Based on animal behavior pharmacology, Prof. Dr. Liu has made the combination of behavior pharmacology-pharmacokinetics –phytochemistry to make drug discover model from herbal medicine, the high automation and intelligent techniques and methods have been established special for evaluating the efficacy and toxicity of herbal medicine on neuropsychological diseases in his group. Prof.&Dr. Liu has been one of core-experts to draft and design national policies and plans on modernization and internationalization of TCM, organized by SATCM and MOST. Prof.&Dr. Liu is currently Principal
        Investigator of international projects to train Ph.D students and young scientists in different university, including the Centre de Recherche Public de la Santé in Luxembourg, the University of British Columbia, Simon Fraser University and Pegasus Pharmaceuticals Inc. in Canada, the Karachi University in Pakistan, as well as the Taipei Physical Education College in Taiwan. Prof.&Dr. has produced 6 Ph.D students and published more than 50 academic papers in the Progress in Neuro-Psychopharmacology and Biological Psychiatry, eCAM, Exp Biol Med., Phytother. Res, Gynecologic Oncology and other domestic and foreign academic journals.

PROFESSOR Jun CHEN
Professor, Ph.D. supervisor of medicinal plants protection
        Dr. Chen serves as a director of Plant Protection of Cultural Centre; She is a expert of Chinese medicine GAP certification of the State Food and Drug Administration, and council member of Branch Section of Association of Promoting Traditional Chinese Medicine, Association of Promoting Chinese herbal medicine GAP and Beijing Entomological Society. She has hosted and participated 46 projects in the National Natural Science Foundation, the “9th five-year”, “10th
five-year”, and “11th five-year” plan projects national science and technology support. So far she has published more than106 academic papers and was compiler member for11 books. She wined 11 prizes for the scientific technological achievement award of Province & Department Level.
        Research interests: Technology on Safety Control of Disease and Pests on Medicinal Plants;Protection and cultivation of endangered Medicinal Plants. Good Agricultural Practice.

PROFESSOR Xian-en LI
Xianen li,The head of the Cultivation Research Center for Medicinal Plants.
        The research interests is mainly focused on plant germplasm evalution and the development of tubers which can be used for Chinese Traditional Medicine.We had accomplished many project which granted by National Natural Science Foundation, National Key Project for Science and Technology.

DOCTOR Xi CHEN
Dr. Chen Xi,Research Associate
        Deputy Director of Development Center & Part-time assistant director of Yunnan branch. He graduated from Heilongjiang University of Chinese Medicine, Tsinghua University, analytical chemistry post-doctoral. In the "Pharmacognosy Magazine", "Planta Med", "Chinese Journal of New Drugs", "Pharmacology and Clinical Pharmacology" and other international and domestic academic journals published more than 10 academic articles.
        Research interests: Chinese medicine in serum chemistry, metabolomics; new formulations
of traditional Chinese medicine; drug, health food and natural plants cosmetics research and development.

PROFESSOR Mei-hua YANG
Dr. Yang Meihua is the deputy director of Analytical Chemistry Center. She received her PhD degree of pharmacognosy from the School of Pharmaceutical Sciences, Peking University in 2001. She undertook post-doctoral research with Professor Zuze Wu at the Beijing Institute of Radiation Medicine (2001-2003). Since 2003, she has worked as a scientist at Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, where she is currently a professor. She has finished or attended 30 research projects financially supported from the Ministry of Science and Technology of China or from
the National Natural Science Foundation of China or from the pharmaceutical company or factory and so on. Now she is undertaking 6 research projects, such as: “The study on the anti-tumor constituents of Justicia procumbens from the Beijing Natural Science Foundation of China (7082060)”; “ The study on the detecting standards of mycotoxins in Traditional Chinese Medicine from Scientific Research Project of Traditional Chinese Medicine Vocation of China in 2008 (200807042)”, and so on. Until now, she has published more than 80 papers in the journals, including Natural Product Reports, Planta Medica and Journal of Pharmaceutical and Biomedical Analysis. Her research interests focus on the bioactive natural products and quality control of traditional Chinese medicine, especially mycotoxin analysis.

PROFESSOR Jun-Shan YANG
Professor Yang Junshan graduated in 1965 from Shenyang Pharmaceutical University,Distribution of the Institute of Materia Medica, Chinese Academy of Medical Sciences. The end of 1992, Professor Yang transferred to the Institute of the Medicinal Plant Development, China Academy of Medical Sciences and Peking Union Medical University and worked as the deputy director and Research Fellow. Since 1993, Professor Yang has enjoyed special government allowances. Now Professor Yang is the Chinese Medical Sciences and Peking Union Medical Academic Committee, Director for the
Centre of Natural Medicine Chemistry in the Institute of the Medicinal Plant Development and PhD supervisor. And he is also the executive director of the Pharmaceutical Society of China, Chinese medicine and natural medicine professional commissions, the "China Pharmaceutical Sciences," deputy editor, "Pharmaceutical Journal," "Natural Medicines", "herbal", "Chinese Drug," "modern medicine and the clinical "and other magazine editors, the State Food and Drug Administration new drug evaluation experts and members of library staff.
        In the 40 years of work, Professor Yang has made some achievements in the areas of basic research for the medicinal plants, chemical, quality standards. He made the effective basis research works on more than 100 kinds of medicinal plants or traditional Chinese medicine chemistry resources, and quality standards, isolation and identification of more than 1700 compounds, of which more than 350 new compounds. Not only clear some of the chemical composition of natural drugs and active ingredients, and traditional medicines based on disease prevention and control of the material, but also the quality of traditional medicines for the development of standards, for the rational use of medicines and development of traditional Chinese medicine again lay good material basis; and to provide a number of lead compounds for drug discovery.
        A class of new drugs in China, "En Bi Pu" (butylphthalide) has been come into the market. Professor Yang made a lot of pioneering research work for it, he was isolated the butylphthalide from celery seed and determine its structure, as will as for its chemical total synthesis, by the rigorous clinical testing to prove for the treatment of epilepsy and stroke can be an effective disease drugs, and declared the patent. "En Bi Pu" is the launch of China in recent years with our own intellectual property rights of a class of innovative medicines, and transferred to Shijiazhuang Hebei Pharmaceutical Factory by 25 million yuan. At the same time this research work awarded of first prize of 2005 Science and Technology Beijing, the Chinese Medical Science and Technology Award, and second prize of 2009 National Science and Technology Progress Award.
        Professor Yang advocate of the better the quality traditional medicine from its source, He is one of the project team leader for "95" key project "Study on the Standardization of Chinese herbal medicines quality standards", head of North China. This research results awarded of "Ninth Five-Year" plan outstanding national key scientific and technological achievements by Science and Technology, Ministry of Finance, State Development Planning Commission, State Economic and Trade Commission. The research work of " quality standards of 66 kinds of Chinese herbal medicines and control article" won the second prize of National Science and Technology Progress Award in 2001.
        Professor Yang published more than 340 research papers in academic journals, of which more than 100 papers were SCI papers, in his 40 years of research work, and has a very significant impact in the subject area. He also hosted and participated in preparation of many important scientific and technological work, mainly on behalf of book, "Analytical Chemistry Handbook." He is currently editor of "Practical Handbook of Natural Medicines," published in nine volumes total.
        Professor Yang have made outstanding achievements in his research work and made some contribution for the modernization of traditional medicine. He was named the outstanding scientific, technical and management experts and gained the recognition and reward, by the Beijing Municipal Committee and Municipal Government of in 2003 in Beijing.
        Professor Yang awarded the outstanding contributions to medicine award by the Chinese Pharmaceutical Development Foundation and the Chinese Pharmaceutical Association, according to his research work in the role of pharmacy in 2009.
        At the same time, he also made in teaching and educating outstanding contributions to the national train a large number of qualified personnel. He has 22 postgraduate training, all graduates; and training 38 PhD students have graduated 36.

PROFESSOR Shan-Fa LU
Shanfa Lu, PhD and Professor
        Dr. Lu is a high-qualified talent recruited by the Institute of Medicinal Plant Development from overseas in 2009. He received his bachelor’s degree in 1991 and master’s degree in 1994 from Beijing Agricultural University where he majored in Plant Physiology & Biochemistry and Plant Physiology, respectively. Dr. Lu had successfully completed the 25th UNESCO International Post-Graduate University Course in Microbiology held from 1997 to 1998 at Osaka University of Japan, and earned his PhD degree in 1999 from the Institute of
Botany, Chinese Academy of Sciences. Dr. Lu had been appointed Research Assistant (1994-1997) and Assistant Professor (1997-2000) at the Institute of Botany, Chinese Academy of Sciences. He had been a Postdoctoral Research Scientist at Michigan Technological University from 2000 to 2002, and a Research Associate (Postdoc) at North Carolina State University from 2002 to 2007. Dr. Lu had served as a Research Assistant Professor at North Carolina State University from 2007 to 2009. He joined the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College in 2009. Dr. Lu was awarded the second prize on Advancement of Sciences and Technology by the Chinese Academy of Sciences (ranked fifth) in 1995. He has published 40 papers in scientific journals, including Plant Cell, Nucleic Acids Research, Plant Journal, Journal of Experimental Botany, Plant & Cell Physiology, and so on, and 2 book chapters. Dr. Lu was a manuscript reviewer for more than 10 international journals, including Plant Cell, Journal of Experimental Botany, Plant Molecular Biology, Planta, Gene, Plant Physiology and Biochemistry, Tree Genetics and Genomes, et cetera, and was a grant proposal reviewer for two international funds, including BARD and BSF. Currently, Dr. Lu serves as an editorial board member for the international journal, GM Crops, and a grant proposal reviewer for the National Natural Science Foundation of China. He has served or is serving as a principal investigator or co-principal investigator on various research projects or sub-projects supported by the Forest Biotechnology Industrial Research Consortium (FORBIRC) at North Carolina State University of USA, the National High-Tech Research and Development Program (863 Program) of China, the Chinese Natural Science Foundation for the Youth, The Scientific Research Foundation of the Chinese Academy of Sciences for Returned Chinese Scholars, The Scientific Research Foundation of the State Human Resource Ministry of China for Returned Chinese Scholars, and the President Foundation of the Chinese Academy of Sciences.
        His current research interests include (1) the biosynthesis and its regulatory mechanism of secondary metabolites in various medicinal plants; (2) the functions of plant small RNAs; (3) the biosynthesis and biotechnology of lignocellulosic materials; and (4) the molecular mechanism of plant responses to stress.

PROFESSOR Ben-Gang ZHANG
Research interests:studies on the medicinal plant resources and cultivation.
        Based on the practical experiences of nearly 30 years, he undertakes a number of national scientific and technological projects, such as “Draft planning and implementation of the Scheme for National survey of traditional Chinese medicine resources”, “Study on international standardization of endangered medicinal plant species planting, harvesting, processing” etc., published over 30 scientific articles, and six academic books specially in traditional
Chinese medicine resources, participated in the State Food and Drug Administration of Traditional Chinese Medicine GAP norms drafting, and the English version translation, and the state registration of new drugs to the English referees, also was invited to the World Health Organization headquarters in Geneva worked on the drafting of Artemisia annua L. (GACP), commitment to national projects are "common, large, endangered resources survey of Chinese herbal medicine" and international cooperation projects with UK and USA in “standardized cultivation research of Chinese herbal medicines in commonly used “.
        Main research interests:
        Medicinal plant resources and conservation
        Botanical garden sciences
        Medicinal plant introduction and cultivation
        Medicinal plant taxonomy
        Rare and endangered medicinal plants research

PROFESSOR Chang LIU
Chang Liu,Professor, PhD
        Deputy Director, Center for Bioinformatics. Dr. Liu obtained graduate degrees from University of Minnesota, Twin Cities with Ph.D. in Molecular and Genomic Parasitology and M.Sc. in Computer Science. He has since then taken serious research positions in GlaxoSmithKline Pharmaceuticals (Research Triangle Park, North Carolina, USA), Visiting Professor (Yale University, Connecticut, USA) and Assistant Professor (University of Hong Kong, Hong Kong). Dr. Liu’s specialties include genome sequencing and analyses and
bioinformatics. His main research interests include using genomic and bioinformatic technologies to understand the mechanisms of the biosynthesis, regulation and therapeutic activities of secondary metabolites derived from medicinal plants. Dr. Liu's was the first one to carry out pilot genome sequencing for Cryptosporidium parvum which laid the foundation for the eventual completion of its genome (Science. 2004. 304:441-445). Later on, he has integrated gene expression profiles with human genome and constructed the CASEG map of human genome. The representative publications are listed below.

PROFESSOR Zhong-Mei ZOU
Prof. Zhong-Mei Zou
        Dr. Zhong-Mei Zou, Deputy Director and Professor of Natural Medicinal Chemistry Research Center at IMPLAD, CAMS PUMC, who has been working in the field of Natural Products Chemistry for over 24 years. She obtained her PhD degree from Peking Union Medical College, and undertook postdoctoral research at Mount Sinai Medical College, USA. Her primary research interests focus on purification and structural identification of naturally occurring compounds which have potentials in treating cancer, age-related and
infectious diseases. She also works on R&D of Chinese herbal medicine products including identification of active constituents, quality control, and efficacy and safety evaluation. Dr. Zou has authored 110 scientific publications.

DOCTOR Yong XIE
Dr. Yong Xie
        2000.4-2005.3 Doctor course student in the Department of Materials Chemistry, Graduated School of Engineering, Osaka University, Japan.
        2005.4-2007.11 Research Associate in the Protein Research Group, Genomic Science Center, RIKEN Yokohama Institute, Japan.
        2007.12-2009.5 Research Fellow in the Structural Biology Search Center, High Energy Accelerator Research Organization, Japan.
        2009.6- Assistant Prof. in the Research Center for Pharmacology and Toxicology, Institute of
Medicinal Plant, Chinese Academe of Medical Sciences & Peking Union Medical College. Since 2010 January, works for as Associate Prof.
        Dr. Xie had mainly performed the crystallographic studies of proteins from 2000 Apr. to 2009 May. Research targets involved the proteins from Hyphomicrobium denitrificans, Thermus Thermophilus, Pyrococcus horokoshii, Plants, Mouse, and Human. Published papers are following:
        (1) Masaki Nojiri*, Yong Xie*, Tsuyoshi Inoue, et al. Structure and function of a novel hexameric copper-containing nitrite reductase. Proc. Natl. Acad. Sci. USA. 104, (2007), 4315-4320.
        *These authors contributed equally to this work.
        (2) Yong Xie, et al. Crystal structure of the minimized ???-hydrolase fold Protein from Thermus Thermophilus HB8. Acta Cryst. F63, (2007), 993-997.
        (3) Yong Xie, et al. Structural Reorganization of the Copper Binding Site Involving Thr15 of Macyanin from Cucurbita pepo medullosa (Zucchini) upon Reduction. J. Biochem. 137, (2005), 455-461.
        (4) Yong Xie, et al. Crystallization and Preliminary X-ray Crystallographic Studies of Dissimilatory Nitrite Reductase isolated from Hyphomicrobium denitrificans A315. Acta Cryst. D60, (2004), 2383-2386.
        (5) Yong Xie, et al. Crystallization and preliminary X-ray crystallographic studies of mavicyanin from Cucurbita pepo medullosa. Acta Cryst. D59, (2003), 1474-1476.
        (6) Hiroyoshi Matsumura, Yong Xie, Shunsuke Shirakata, Tsuyoshi Inoue, Takeo Yoshinaga, Yoshihisa Ueno, Katsura Izui, and Yasushi Kai. Crystal Structures of C4 Form Maize andQuaternary Complex of E. coli Phosphoenolpyruvate Carboxylases. Structure 10, (2002), 1721-1730.
        (7) Tsuyoshi Inoue, Shinnichiro Suzuki, Nobuya Nishio, Kazuya Yamaguchi, Jiro Tobari, Xie yong, Sawako Hamanaka, Hiroyoshi Matsumura, Yasushi Kai. The Significant of the Flexible Loop in the Azurin (Az-Iso2) from the Obligate Methylotroph Methylomonas sp. Strain J. J. Mol. Biol. 333, (2003), 117-124.
        (8) Yousuke Okano, Eiichi Mizohata, Yong Xie, Hiroyoshi Matsumura, Hajime Sugawara, Tsuyoshi Inoue, Akiho Yokota, and Yasushi Kai. X-ray Structure of Galdieria Rubisco Complexed with One Sulfate Ion per Activite Site. FEBS letters 527, (2002), 33-36.
        (9) Heitato Yamane, Yasuo Nakao, Satoru Kawabe, Yong Xie, Nobuko Kanehisa, Yasushi Kai, Masashi Kinosita, Wasuke Mori, and Yasushisa Hayashi. Synthesis, Structures and  [(1-ethyl-2-benzimidzolyl)-methyl]-2-hydroxy-1,3-diaminopropane and their Urea Complexes Relevant to the Urease Active Site. Bulletin of the Chemical Society of Japan 74, (2001), 2107-2112.         
        Current Research Plan
        (1) Studies of three-dimensional structure of drug-target proteins isolated form Mycobacterium tuberculosis H37Rv.
        (2) Structural biology studies of DNA-binding Proteins.
        (3) Studies of three-dimensional structural diversity of isoenzyme.

DOCTOR Yao HUI
Dr.Hui Yao
        Assistant professor and associate professor, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences (2008.11- present);Post-doctoral fellow, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences (2006.9-2008.10).Ph. D. in Pharmacognosy, School of Pharmacy, Fudan University, 2006,M.S. in Botany, College of Life Science, South China Agricultural University; 2003,B.S. in Biotechnology, Department of Biology, Northwest University, 1998
        Research Interests:Molecular Identification of TCM: Selection and evaluation of candidate DNA barcoding sequences and authentication of TCM using DNA barcoding technique.Functional Genomics of Chinese medicine: Gene cloning and identification on the key enzymes involved in biosynthesis of active constitutes in medicinal plants.
        Correspondence
        Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences
        No. 151, Malianwa North Road, Haidian District, Beijing 100193, China
        Phone: 0086-10-62899727
        E-mail: hyao@implad.ac.cn
        Publications
        Chen Shi-Lin, Yao Hui, Han Jian-Ping, Liu Chang, Song Jing-Yuan, Shi Lin-Chun, Zhu Ying-Jie, Ma Xin-Ye, Gao Ting, Pang Xiao-Hui, Luo Kun, Li Ying, Li Xi-Wen, Jia Xiao-Cheng, Lin Yu-Lin, Leon Christine. Validation of the ITS2 Region as a Novel DNA Barcode for Identifying Medicinal Plant Species. PLoS ONE, 2010, 5(1): e8613.
        Yao H, Song JY, Ma XY, Liu C, Li Y, Xu HX, Han JP, Duan LS, Chen SL. Identification of Dendrobium Species by a Candidate DNA Barcode Sequence: the Chloroplast psbA-trnH Intergenic Region. Planta Medica, 2009, 75: 667-669
        Song JY, Yao H, Li Y, Li XW, Lin YL, Liu C, Han JP, Xie CX, Chen SL. Authentication of the family Polygonaceae in Chinese pharmacopoeia by DNA barcoding technique. Journal of Ethnopharmacology, 2009, 124: 434-439
        Yao H, Zhao Y, Chen DF, Chen JK, Zhou TS. ISSR primer screening and preliminary evaluation of genetic diversity in wild populations of Glycyrrhiza uralensis. Biologia Plantarum, 2008, 52: 117-120
        Li Ying, Luo Hong-Mei, Sun Chao, Song Jing-Yuan, Wu Qiong, Wang Ning, Yao Hui, André Steinmetz, Chen Shi-Lin. EST analysis based on 454 transcriptome sequencing reveals putative genes involved in glycyrrhizin biosynthesis. BMC Genomics, 2010. (In Press).

DOCTOR Jing-Yuan SONG
Ph.D, Deputy Director of Medicinal Plant Authentication Centre
        Jingyuan Song earned his Ph.D. at Peking Union Medical College in Beijing (2002) and his post doctor at North Carolina State University in the United States of America (2004-2006). He took a fellowship of Beijing Nova Program in 2003. For over ten years, he has performed a lot of projects supported by enterprises, national and local governments, such as National Natural Science Foundation of China, the International Cooperation Program of Science and Technology, the Special
Foundation of Ministry of Health, National Key Technologies R&D Program, Beijing Municipal Natural Science Foundation, Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine CO. LTD., Tsumura & CO of Japan.
        Jingyuan Song has established authentication system of medicinal plants using DNA barcoding technique and platform of functional genes discovery based on expressed sequence tags. He first applied the uniform design to in vitro production of active components in medicinal plants. In study on symbioses of Orchidaceae, he made important contribution according to microstructure, ultrastructure and mRNA different display reverse transcribed polymerase chain reaction. He has published five books and about sixty papers in PLoS ONE, BMC genomics, Plant Cell Physiology, Cladistics, Planta, Physiologia Plantarum, Process Biochemistry, Journal of Ethnopharmacology, Plant Cell Reports, Planta Medica, Science China Life Sciences and so on.
        His research interests include authentication of medicinal plants by DNA barcoding technique, functional genomics of medicinal plants, tissue culture and production of active components.

PROFESSOR Wei-Wei GAO
Weiwei Gao, professor, serves as the Director of the department of molecular ecology in the biotechnology research center, Chinese Academy of Medical Science, and vice-director of Yunnan Branch, obtained her Ph.D. on Pharmacognosy in Peking Union Medical College and as a visiting professor received molecular biotechnology training in the University of Texas Medical Branch in 2007. She is the appraisal expert of the State Food and Drug Administration (SFDA), and the National Natural Science Fund of P. R. China. She holds a concurrent post of standing director of Beijing
Society for Plant Pathology, and member of International Allelopathy Society. Research work including drug development of Chinese traditional medicine, evaluation and identification on medicinal plants' germplasm resources; control technology of harmful fungus affecting Chinese medicinal plant yield and quality; and allelopathy of Chinese medicinal plant. She published more than 70 sc
        ientific papers in Chinese and International Academic journals such as Plant and Soil, Journal of Applied Microbiology, and 2 monographs as the chief editor; received national and provincial awards for the scientific outcomes of 5 projects, and 3 patents.
        Research Interests: Plant Chemoecology; Allelopathy and the integrated control measures of plant disease and pest, Quality control of Chinese medicinal materials and natural products development
        Research Publications:
        1. X.B.BI, J.X.YANG and W.W.GAO*. Autotoxicity of phenolic compounds from the soil of American ginseng (Panax quinquefolium L.) Allelopathy J. 2010, 25(1): 115-122 (2008 IF 0.525)
        2. Yang Dan, Hai-Yan Liu, Wei-Wei Gao*, Shi-Lin Chen. Activities of essential oils from Asarum heterotropoides var. mandshuricum against five phytopathogens. crop protection. 2010, 29: 295-299 (2008 IF 1.2)
        3. Chun Nian He,Wei Wei Gao*,Jia Xue Yang,Wu Bi,Xue Song Zhang,Yang Jing Zhao. Identification of Autotoxic Compounds from Fibrous Roots of Panax quinquefolium L. plant and soil,2009,318:63-72 (2008-IF 1.998)
        4. Luo, Y., Gao, W., Doster, M. and Michailides, T.J. Quantification of conidial density of Aspergillus flavus and A. parasiticus in soil from almond orchards using real-time PCR. Journal of Applied Microbiology. 2009 106(5):1649-60.(2008-IF 2.001)
        5. 杨家学 焦晓林 高微微*. 西洋参根部病害研究进展,植物保护,2009,35(6):30-35
        6. 杨家学,高微微*. 酚酸类化感物质对2种西洋参病原真菌的作用,中国农学通报,2009,25(9):207-211
        7. 徐文燕,高微微*,何春年,佟建明*.紫花苜蓿不同品种和不同季节黄酮量的比较研究 中草药,2009,40(5):815-817
        8. 李荣英,彭建明,高微微*. 阳春砂仁植株新株萌发与叶枯病发生的关系,中国中药杂志,2009,34(12):1588-1590
        9. 李安英,张潞生*,高微微*,王程亮,王红清,杨小柳. 草莓根际土壤微生物DGGE研究中DNA模板的制备, 农业生物技术学报,2009,17(4):701-706
        10. 高微微主编,中药材生产技术,2009,北京:中国农业出版社
        11. 高微微*,焦晓林,毕武,何春年. 罹病西洋参根内主要人参皂苷含量的变化. 中国中药杂志, 2008. 33(24): 2905-2907
        12. XU Wen-yan1,GAO Wei-wei1*,HE Chun-nian1,TONG Jian-ming2*. Chemical Constituents from the Aerial Part of Medicago sativa L. Natural product research and development (天然产物研究与开发),2008,(6):1005-1007
        13. XF Dong, WW Gao, JM Tong,* H. Q. Jia, R. N. Sa, and Q. Zhang. Effect of Polysavone (Alfalfa Extract) on Abdominal Fat Deposition and Immunity in Broiler Chickens. Poultry Science 2007, 86:1955–1959 ( 2007 SCI 1.747 )
        14. 高微微,赵杨景,王玉萍,陈士林*.我国药用植物栽培地的可持续利用研究.中国中药杂志,2006. 31(20):1665-1669

DOCTOR Xiang-Tao WANG
Dr.Xiang-tao Wang,phD, Associate Professor
        deputy –Director of the Department of Scientific Research.After graduation from Department of Pharmacy, Henan College of TCM in 1994 with a bachelor degree, Dr Wang went to Heilongjiang University of TCM for his master degree in natural product chemistry and then went to School of Pharmacy, Peking University for his doctoral degree. Dr Wang start his postdoctoral research on liver-targeted pro-drug delivery system in Oxford University from 2003 to 2004 and then went to Wayne State University for further research on
dendrimer-based drug delivery system. Since his joining IMPLAD in May 2006, Dr Wang has been working in the Drug Delivery Center and was appointed in 2009 as deputy-Director of the Department of Scientific Research. During this period of time, Dr Wang has undertaken two NNSFC (National Natural Science Foundation of China) projects, one ISTCP (International S&T Cooperation Program of China) project and one Beijing NSF (Beijing National Science Foundation) project and was received in Beijing S&T Star Training Program. Dr Wang is also a SFDA expert and an editorial member of Chinese Journal of Pharmacentical Technolgy Economics & Management. Dr Wang has published over 30 papers in domestic and international journals such as Bioconjugate and PNAS.
        Dr Wang's research interests cover: 1. Particulate-based drug delivery system including liposomes, nanoparticles, micelles, emulsions, microspheres, nano-suspensions and micro-suspensions. 2.Targeted drug delivery, sustained or controlled drug release on basis of dendrimers. 3. Transdermal drug delivery, especially the delivery and assessment of multi-component drug system. 4.Sustained release on basis of in situ gel system. 5. Synthesis of pharmaceutical macro-molecules and novel functional polymers and their application in drug delivery system. 6. Drug discovery from TCM and the application of novel dosage from and novel technology in TCM.

PROFESSOR Xiao-Jun MA
Prof.Xiao-jun Ma
        Research interests: Evaluation of medicinal plant germplasm resources,breeding of medicinal plant.

DOCTOR Zhi-Hua LIU
Dr. Zhihua Liu
        Zhihua Liu Ph.D./Associate Professor/Graduate Supervisor
        Zhihua Liu was actively engaged in Bioinformatics and Biostatistics research in Harvard University and Dana-Farber Cancer Institute. He published about 10 academic articles as the first author in peer-reviewed international journals and was honored for Outstanding Scientific Article in Life Sciences. He focused primarily on mathematical modeling of biological problems, statistical analysis of biological data, developing software and web
server. He has managed and participated in China Medical Board (CMB), National Science Foundation, International Cooperation Project of the Ministry of Science and Technology, National “863” Project and so on. He served as peer reviewer for "Applied Mathematics and Computation" and other international journals. He got involved in translating book titled "Fundamental Concepts of Bioinformatics" and attended international conference such as Emerging Quantitative Issues in Parallel Sequencing (EQuIP-Seq), The International Bioinformatics Workshop, The International Conference on Bioinformatics and Biomedical Engineering, International Conference on Life System Modeling and Simulation.
        Zhihua Liu was hired into tenured faculty position at the level of associate professor through the project of Brain Gain at the Institute of Medicinal Plant Development (IMPLAD), affiliated with the Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC). Furthermore, he passed the certification of senior professional title of the Ministry of Health of China. He received grant from CMB (http://www.chinamedicalboard.org/) shortly after he joined IMPLAD and became the first researcher who got this prize fund in the history of IMPLAD. Now his main research interests span a broad range of topics in plant barcode, cancer bioinformatics and next-generation sequencing data analysis. He is also in charge of international Herb Barcode of Life organization's website.
        Main research directions: Bioinformatics, Pharmaceutical informatics, Medical informatics, Genome informatics, Evolutionary informatics
        Main operating system platform: Linux, Mac OS X, Solaris, AIX and Windows
        Main programming language: Python, C/C++, Java
        Main analytical tool: Matlab, R/BioConductor, EMBOSS

PROFESSOR Chun-Lan WANG
Prof. Chun-lan Wang
        Chun-lan Wang, who had graduated from Chemistry Department of Shanxi University, and then pursued a further study in Beijing Medicine School, is a master instructor and researcher of Analysis Center. Up to now, Wang has published more than fifty theses, and acquired six patents.
        Main research direction: extraction and identification chemical proponents of medicine plant and fungi, qualification of them.

PROFESSOR Da-Yong CAI
Dayong Cai,PhD & MD, Associate professor, Supervisor of graduate for mastership. Members of Editor Board for Chinese Journals as China Pharmacist, Edit-in-chief of Science of Traditional Chinese Prescription or Diagnostics of Traditional Chinese Medicine, Members of Editor Board for Chinese textbooks as Chinese medicine Pharmacology or pathology. Responsible for 16 researching programs, such as Key Project of Chinese National Programs for Fundamental Research and Development (973 program), Chinese National Programs for Science and
Technology Development, The 11th Five Years Key Programs for Science and Technology Development of China, National Science Foundation for Distinguished Young Scholars, National Science Foundation for Post doctors, and Chinese National Natural Science Foundation. 96 articles have published in special journals. Major researching works include the pharmacology and toxicology of cardiovascular system, neoplasm, digestive system, and neural system. Having took part in setting up the platform of systems biology for Chinese Medicine, responsible for the pathological findings matching with the findings from genomics, transcriptomics, proteomics, and metabonomics. Having been responsible for maintaining the model animals database for human diseases.
        Recent Published articles:
        1. Q Hua, X Zhu, P Li, H Tang, D Cai, Y Xu, X Jia, J Chen, and Y Shen. Refined Qing Kai Ling, traditional Chinese medicinal preparation, reduces ischemic stroke-induced infarct size and neurological deficits and increases expression of endothelial nitric oxide synthase. Biol Pharm Bull, 2008; 31(4): 633-7.
        2. DY Cai, F Yu, W Jiang, HF Jiang, CS Pan, YF Qi, L Chang, J Zhao, JH Yang, MJ Zhu, YX Jia, B Geng, TM Ma, YZ Pang, and CS Tang. Adrenomedullin(27-52) inhibits vascular calcification in rats. Regul Pept, Jul 2005; 129(1-3): 125-32.
        3. CS Pan, JH Yang, DY Cai, J Zhao, H Gerns, J Yang, JK Chang, CS Tang, and YF Qi, Cardiovascular effects of newly discovered peptide intermedin/adrenomedullin 2. Peptides, Sep 2005; 26(9): 1640-6.
        4. W Jiang, DY Cai, CS Pan, YF Qi, HF Jiang, B Geng, and CS Tang. Changes in production and metabolism of brain natriuretic peptide in rats with myocardial necrosis. Eur J Pharmacol, Jan 2005; 507(1-3): 153-62
        5. WH Ding, SY Chu, HF Jiang, DY Cai, YZ Pang, CS Tang, and YF Qi. Plasma mitochondrial coupling factor 6 in patients with acute myocardial infarction. Hypertens Res, Oct 2004; 27(10): 717-22.
        6. W Jiang, HF Jiang, DY Cai, CS Pan, YF Qi, YZ Pang, and CS Tang. Relationship between contents of adrenomedullin and distributions of neutral endopeptidase in blood and tissues of rats in septic shock. Regul Pept, May 2004; 118(3): 199-208.
        7. W Jiang, HF Jiang, CS Pan, DY Cai, YF Qi, YZ Pang, and CS Tang. Relationship between the contents of adrenomedullin and distributions of neutral endopeptidase in blood and tissues of spontaneously hypertensive rats. Hypertens Res, Feb 2004; 27(2): 109-17.
        8.YF Jiang, QH Wang, ZQ Liu, Q Wang, DY Cai, SJ Liu, Y Zhang, and QF Huang. Effects of salvianolic acid B on cerebral energy charge and activity of ATPase in mice with cerebral ischemia.Zhongguo Zhong Yao Za Zhi, Sep 2007; 32(18): 1903-6.
        9.DY Cai, JX Chen, W Zhang, X Wang, LP Sun, JJ Zhang, and QF Huang. Protective effect of Danzhi-xiaoyao San on rat brain energy or material metabolism (correction of matebolism) dealt with D-galactose. Space Med Med Eng (Beijing), Feb 2005; 18(1): 32-6.
        10.DY Cai and CS Tang. Protective role of neutral endopeptidase in cardiovascular diseases. Sheng Li Ke Xue Jin Zhan, Jan 2005; 36(1): 53-4.
        Tel:086-010-62899771;E-mail:dycai@implad.ac.cn,beijingcdy@yeah.net,          beijingcdy@msn.com

PROFESSOR Yong-Hong LIAO
Prof. Yong-Hong Liao
        Deputy Director of the Formulation Research Center.Yong-Hong Liao received his B.S.from Tsinghua University in physical chemistry in 1991 and Ph.D. from King’ College London, University of London in pharmaceutics in 2002. Dr. Liao research is focused on the biopharmaceutical characterization of natural products and novel drug delivery systems that facilitate efficient topical administration of therapeutic agents intended for the treatment of respiratory diseases and cancers, with a specialization in bioanalytical method
development and validation (HPLC & LC/MS), rational design and evaluation of of metered-dose inhalers and sustained release formulations.
        Selected Publications:
        1)Ye Jun-Xiao, Wang Wei, Quan Li-Hui, Liu Chun-Yu, Chang Qi and Liao Yong-Hong, 2010, An LC-MS/MS method for the simultaneous determination of chlorogenic acid, forsythiaside A and baicalin in rat plasma and its application to pharmacokinetic study of Shuang-huang-lian in rats, Journal of Pharmaceutical and Biomedical Analysis, 52(4): 625–630
        2)Xiao-Bin Liu, Ye Jun-Xiao, Li-Hui Quan, Chun-Yu Liu, Xu-Liang Deng, Ming Yang and Yong-Hong Liao, 2008, Pulmonary delivery of scutellarin solution and mucoadhesive particles in rats, European Journal of Pharmaceutics and Biopharmaceutics, 70:845-852.
        3)Sin Ting Lau, Zhi-Xiu Lin, Yong-Hong Liao, Ming Zhao, Christopher H.K. Cheng, Po Sing Leung, 2009, Brucein D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase. Cancer Letters 281: 42–52.
        4)Chun Wang, Li-Hui Quan, Yi Guo, Chun-Yu Liu and Yong-Hong Liao. 2007. Uptake and biodistribution of rizatriptan to blood and brain following different routes of administration in rats,International Journal of Pharmaceutics,304 (1-2): 29-39.
        5)Yong-Hong Liao, Marc B. Brown, Stuart Jones,Tahir Nazir and Gary P. Martin, 2005, The effects of polyvinyl alcohol on the in vitro stability and delivery of spray-dried protein particles from surfactant-free HFA 134a-based pressurised metered dose inhalers. International Journal of Pharmaceutics, 304 (1-2): 29-39.
        6)Yong-Hong Liao, Stuart Jones, Ben Forbes, Marc B. Brown and Gary P.Martin, 2005, Hyluronan: Pharmaceutical Characterization and Drug Delivery, Drug Delivery, 6(12): 327-342.
        7)Yong-Hong Liao, Marc B. Brown, Tahir Nazir, Abdul Quader and Gary P. Martin. 2002. Effects of sucrose and trehalose on the preservation of the native structure of spray-dried lysozyme. Pharm. Res. 19: 1849-1855.
        8)Yong-Hong Liao, Marc B. Brown, Abdul Quader and Gary P. Martin. 2002. Protective mechanism of stabilising excipients against dehydration in the freeze-drying of proteins. Pharm. Res. 19: 1854-1861.

PROFESSOR Bao-Lin GUO
Prof. Bao-lin Guo
        Baolin GUO Ph.D Professor tutor of postgraduate candidates Vice Director of Medicinal Plants Identification Center.
        Doctor of medicine from Chinese Academy of Medical Sciences in 1999. Member of Professional Committee of Medicinal Plants and Herbs of Botanic Society of China, Professional Committee of Chinese Medicine Resources and Ecology of Ecologic Society of China, Council member of Botanic Society of Beijing. Editorial committee member of the magazines,”Chinese Materia
Medica”,”ChineseTraditional and Herbal Drugs”. More than 100 papers published in the magazines of“J Chromatography A”,“Phytochemistry”,“Spectrochimica Acta Part A”,” Journal of Systematics and Evolution”“Chinese Materia Medica”,”ChineseTraditional and Herbal Drugs”.etc.
        Direction of Research: Sustainable utilization of medicinal plants, Herb identification and quality control, Taxonomy and chemotaxonomy of medicinal plants.

PROFESSOR Zhao ZHANG
Prof.Zhao Zhang
        Research interests:Medicinal plant conservation,focus on rare and endangered medicinal plant species.Studies on medicinal plant introduction,taxonomy and reproductin works etc.
        1983 Graduated from Yunnan University, Department of Plant Biology. In the same year to work in the Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences, and received a master's degree of Peking Union Medical College in 1994. Commitment and participation in a number of research projects which
supported from Ministry of Science and technology, Administration of Traditional Chinese Medicine, Economic and Trade Commission, the World Health Organization and the Beijing Municipal Education Commission Key Disciplines, specially interested in rare and endangered medicinal plants, and has in-depth study on the system of caused a species crisis, and used to introduction and domestication of medicinal plants. ", published more than 20 research papers in "Wuhan Botanical Research", "Biological diversity ",”Chinese Herbal Medicine”、“China journal of Chinese materia medica“、"China Botanical Garden" and other international and domestic academic journals, as co-editor and participant, seven academic books were published. Research interests: the protection of medicinal plant germplasm resources, rare and endangered medicinal plants conservation, collection and breeding of plant species, medicinal plant taxonomy, introduction and domestication of medicinal plants.

PROFESSOR Xu-Dong XU
Prof.. Xu-dong Xu
        As the Director of Chinese Medicine Resources Chemistry Laboratory of Medicinal Chemistry Research Center, Xudong Got the Ph.D degree from Peking Union Medical College. Dr. Xu did the post-doctoral research in the College of Pharmacy of the University of Illinois at Chicago from 2001 to 2003. Committee Member of Natural Medicinal Chemistry of Beijing Pharmaceutical Society, As a Project Leader assumed 2 projects supported by the National Natural Science Foundation of China, 1 projects supported by Ministry of National Education
Fund for Returned overseas Students, 1 project supported by the Scientific Research Foundation for the Returned Overseas Chinese Scholars from the State Administration of Traditional Chinese Medicine, 1 project supported by the Beijing Natural Science Foundation and 1 project for the States Pharmacopoeia standards revised 2010 version of Chinese medicines; As a Sub-Project Leader attended 1 project for the National Scientific and technological research projects, 2 project supported by the development of new drugs in the Eleventh Five-Year "Significant New Drugs Created" Science and Technology Major Projects, 3 projects supported by the National Natural Science Foundation of China, 2 project supported by the special purpose of basic scientific research operation grant for commonweal academy and institute of central authorities, 2 project supported by the TCM industry research special, 1 project supported by the Key project of Beijing Natural Science Foundation and 1 project supported by the Science and Technology Grant of Guangxi Province. More than 40 papers had been published in J. Nat. Prod, Chem. Res. Toxicol, Chem. Pharm. Bull,Heterocycles, Chim. Chem. Lett,Natural Product Research, Europen Journal Of Drug Metabolism And Pharmacokinetcs, Journal Pharmaceutical and Biomedical Analysis, Acta Botanica Sinica, Acta Pharmaceutica Sinice,China Journal of Chinese Materia Medica, Chinese Pharmaceutical Journal, and other international and domestic academic journals. Participate in the preparation of 3 academic works and 6 national patent applications. As the main participants got access to the Chinese Ministry of Science and Technology Progress Award and the Global AIDS Foundation STD outstanding performance prize awarded in 1992 for the Key project of Chinese Academy of Medical Sciences, "Integrated application of basic research licorice - AIDS research" work.
        Research interest: Major in natural products chemistry and new Traditional Chinese Medicine and functional food development; and isolation and characterization of activity constituents from Traditional Chinese Medicine and evaluation of their quality.

PROFESSOR Wan-long DING
Professor Wan-Long Ding:
        Professor Ding graduated from College of Plant Protection, Shenyang Agricultural University, and then working in Plant Protection Lab of Medicinal Plant Cultivation Research Center until now. So far, more than ten projects have been presided and finished successfully, such as the National Natural Science Foundation of China, The National Key Technologies R&D Program of China, the National Sciences & Technology Pillar Program, Research project of State Administration of Traditional Chinese Medicine, etc. More than forty research
papers, such as Chinese Traditional and Herbal Drugs, Biochemical Genetics, etc., have been published in national and international journals. And also, five works including Phytopathology of Medicinal Plants have been published, and wined four provincial and ministerial level scientific researsh achievement awards yet.
        Field of research:
        Medicinal plant diseases and control technology
        Pollutant-free cultivation and wildlife tending of Chinese Herbal medicines

PROFESSOR Qi CHANG
Prof. Qi Chang
        Dr. Chang received her B.Sc. from Xi’an Medical University in 1984 and had been worked in Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences. She received her Ph.D degree from School of Pharmacy, The Chinese University of Hong Kong (CUHK, 1998-2002). After finishing two-year post-doctoral research on pharmacokinetics of TCM components at CUHK, Dr. Chang started her career in teaching and research in IMPLAD. She engaged in several projects supported by MOST of China in recent
years, such as new drug development program “Development of Ge-Tong Tong-Luo capsule”; and international S&T cooperation projects “The anticancer effect of Kampo medicine and its related mechanisms” and “The active components and mechanisms of cognitive benefits by Kaixinsan”. Dr Chang's current research projects include International S&T Collaboration Project “Preparation of nanofiber delivery system of TCM” and National S&T Major Project “Pharmacokinetic methodology for TCM”. She has totally published more than 60 scientific articles.
        Research areas:
        Identification of in vivo active components of TCM
        Pharmacokinetic properties (ADME) of TCM components
        Mechanism of intestinal transportation of TCM components
        Herb-drug interactions
        Selected publications
        Wang GN, Pan RL, Liao YH, Chen Y, Tang JT, Chang Q. An LC-MS/MS method for determination of forsythiaside in rat plasma and application to a pharmacokinetic study. J Chromatogr B 2010:878 (1):102-106.
        Chen Y, Liu XM, Pan RL, Wang GN, Fu Y, Chang Q. An LC-MS/MS method for determination of 3,6'-disinapoylsucrose in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2009, 23 (12):1326-1332.
        Chang Q, Chow MS, Zuo Z. Studies on the influence of esterase inhibitor to the pharmacokinetic profiles of oseltamivir and oseltamivir carboxylate in rats using an improved LC/MS/MS method. Biomed Chromatogr. 2009; 23: 852–857.
        Xi J, Chang Q, Chan CK, Meng ZY, Wang GN, Sun JB, Wang YT, Tong HH, Zheng Y. Formulation Development and Bioavailability Evaluation of a Self-Nanoemulsified Drug Delivery System of Oleanolic Acid. AAPS PharmSciTech. 2009;10 (1):172-182.
        Ma KY, Zhang ZS, Zhao SX, Chang Q, Wong YM, Yeung SYV, Huang Y, Chen ZY. Red yeast rice increases excretion of bile acids in hamsters. Biomedical and environmental sciences, 2009, 22: 269-277.
        Chang Q, Sun L, Zhao RH, Chow MSS, Zuo Z: Simultaneous determination of ten active components in traditional Chinese medicinal products containing both Gegen (Pueraria lobata) and Danshen (Salvia miltiorrhiza) by high performance liquid chromatography. Phytochemical analysis. 2008, 19(4):368-375.

PROFESSOR Jian-yong SI
Prof. Jian-yong Si
        Jian-yong Si has got his Ph. D. in Institute of Medicinal Plant Development, Chinese Academy of Sciences. He is currently the deputy director of XinJiang Branch, XinJiang Institute of Chinese Materia Medica and Ethnical Materia. Dr. Si has published 80 research papers, applied 10 patents(seven of them were approved), and written 3 book chapters.
        His group mainly focuses on the secondary metabolites in traditional herbal medicinal plants and folk medicine. Our goal is to clarify the chemical
essence of traditional usages of Traditional Chinese Medicine and folk herbs, as well as to find potential pharmaceutical lead compounds through isolation, identification, modification, chemistry synthesis and establishing a structure-activity relationship, some new drugs with following effects are developed.

DOCTOR Chun SUI
Dr. SUI Chun,
        In 2006, Ph. D. graduated from College of Agronomy and biotechnology, China Agricultural University. From Sep. 2006 to Oct. 2008, researching as a postdoc at Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union of Medical College. Researcher CHEN Shi-lin and researcher WEI Jian-he are the co-mentors. The research project is studying on ISSR and SSR molecular marker techniques and construction of a full-length enriched cDNA library for medicinal Bupleurum. At
present, work at Center of Medicinal Plant Cultivation in the same Institute after finishing postdoctoral research, mainly engaged in secondary metabolism of medicinal plant. Taking charge of and participating in several funds and projects, such as Beijing Municipal Natural Science Foundation, China (No. 5102033), Chinese Postdoctoral Science Foundation Second Reward (No. 20070410615), Special Funds in Basic Scientific Research for Non-Profit Research Institutes Financed by Ministry of Finance People's Republic of China (No. YZ-1-10), National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science & Technology of China (No. 2006BAI09B01), etc.

DOCTOR Lin-fang HUANG
Dr. Huang Linfang
        Dr. Huang Linfang, female, is an Associate Professor of Institute of Medicinal PlantDevelopment at Chinese Academy of Medical Sciences & Peking Union Medical College. Her research direction is Pharmacognosy, and research interests focus on the following field: ① the identification and quality evaluation of medicinal plants.② varieties of medicinal plant resources, resource quality and ecological environment-related research.③ varieties of medicinal plant resources, resource quality and genetic resources-related research. She oversees
several nationally-funded projects. These have included the national level projects form the Chinese Pharmaceutical Industry R & D Project, Project of Chinese Medicine Herb from Development and Reform Commission. In 2005, a 2-year international grant was received form Japan International Science and Technology Exchange Center and from the Ministry of Education, Science, Sports and Culture of Japan (JISTEC) for Young Scientists B: 18790378 to support the postdoctoral research.
        Dr. Huang has published over 30 scientific articles focused on phytochemistry, Parmacology and many of them published in SCI Journal, such as Journal of Ethnopharmacology, Biochemical and Biophysical Research Communications, Pharmacology, Biochemistry and Behavior. She has participated in compiling 2 monographs "Introduction for sustainable utilization of resources of Chinese Medicine herb," and "Theory, Methods and Practice for quality Investigation of Chinese Medicine herb".
        The following are selected publications:
        1. Linfang Huang, Akio Koizumu; Megumi Toyoshima; Akihiro Asakawa; Kayoko Inoue; Kouji Harada; Shilin Chen; Tomomi Kinoshita, Levels of N-acylethanolamines in O,O,S-trimethylphosphorothioate (OOS-TMP)-treated C57BL/6J mice and potential anti-obesity, anti-diabetic effects of OOS-TMP in hyperphagia and hyperglycemia mouse models Pharmacology, Biochemistry and Behavior 92 (2009) : 1–5.
        2. Linfang Huang, Toru Yagura, Shilin Chen,Sedative activity of hexane extract of Keampferia galanga L. and its active compounds.Journal of Ethnopharmacology 120 (2008) :123–125.
        3. Linfang Huang,Megumi Toyoshima, Kouji Harada, Akihiro Asakawa, Kayoko Inoue, Akio Koizumi,Roles of neuropeptides in O,O,S-Trimethylphosphorothioate (OOS-TMP)-induced anorexia in mice. Biochemical and Biophysical Research Communications 2007, 362(1): 177-182.
        4. Linfang Huang, Megumi Toyoshima, Kouji Harada, Akihiro Asakawa, Kayoko Inoue, Akio Koizumi Endocannabinoids levels and anorexia rat induced by O,O,S-Trimethylphosphorothioate (OOS-TMP). Japanese Journal of Hygiene. 2007,62 (2): 468.
        5. Linfang Huang, Caixiang Xie, Shilin Chen, Baozhong Duan et al. Regional suitability evaluation on desert herba Cynomorii. Chinese Bulletin of Botany. 2010,45(2):205-211.
        6. HUANG Lin-fang, CHEN Shi-lin, LIUHui, WANG Li-zhi, et al. Determination of three Alkaloids in Different Processing Methods on Fritillaria cirrhosa by HPLC-ELSD Method. Chinese traditional patent medicine. 2009,31(10):1560-564.
        7. LIU Hui, HUANG Lin-fang, CHEN Shi-lin, WANG Li-zhi et al. Study on the optimal collection period of Semi-wild cultivated Fritillaria cirrhosa D. Don. Journal of Chinese Medicinal Materials 2009, 32(8)331-332.
        8. CHEN Shi-lin,SU Gang-qiang, HUANG Lin-fang The sustainable development framework of national Chinese medicine resources China Journal of Chinese Materia Medica 2005, 30(8):17-23.
        9. WAN De-guang ,HUANG Lin-fang Determination of Effective Compounds Oleanoli Acid in Ku-ding-cha From SiChuan Province by HPLC Journal of Chengdu University of Traditional Chinese Medicine 2003,26 (4): 43-45.
        10.CHEN Shi-lin, WEI Jian-he,HUANG Lin-fang Probing into the Theory and Practice of Medicinal Materials Wildlife Tending. China Journal of Chinese Materia Medica. 2004,29(12):1123-1125.
        11. HUANG Lin-fang, WAN De-guang Resources Investigation and Identification of Ku-ding-cha From SiChuan Province Research and Practice of Chinese Medicines 2003,17(1): 56-57.
        Institute of Medicinal Plant Development (IMPLAD),
        Chinese Academy of Medical Sciences (CAMS)
        No.151, Malianwa North Road, HaiDian District
        Beijing 100193
        P.R. China
        Tel: +86-10-62811448
        Website: http://www.implad.ac.cn
        E-mail: lfhuang@implad.ac.cn

PROFESSOR Yong PENG
Dr. Yong PENG
        Prof. PENG is the assistant director of Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences & Peking Union Medical College and the head of Research Centre of Pharmacophylogeny. He obtained his Ph.D Degree at School of Chinese Medicine, Hong Kong Baptist University. He is the board members of International Society for Ethnopharmacology and has acted as the expert for evaluation in health food and International cooperation projects concurrently. Prof. PENG also serves as member of the editorial
board for Journal of Chinese Materia Medica, Modern Chinese Medicine, etc.. He has published more than 50 scientific articles and 6 books. Prof. PENG specializes in Ethnopharmacology, medicinal plant resources and informatics research and development.
        Tel: +86-10-62894462
        E-mail: ypeng@implad.ac.cn

DOCTOR Zheng ZHANG
Ph.D Zheng Zhang
        Dr. Zheng Zhang is assistant professor and the assistant director of Hainan Branch of Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College (PUMC). His research interests are focused on the mechanisms of agarwood formation in Aquilaria sinensis and the technologies of quick, effective sustainable and artificial inducement of resin in A. sinensis. He is currently working on four projects, including the National Key Project of Scientific and Technical Supporting Programs
Funded by Ministry of Science & Technology of China, the Science Foundation for The Excellent Youth Scholars of Ministry of Education of China, the Beijing Municipal Natural Science Foundation and the Scientific Research Personnel Servicing for Enterprises Programs Funded by Ministry of Science and Technology of the People's Republic of China. He has applied for three patents about technologies of artificial inducement of resin in A. sinensis. He has published over 20 academic papers, including six SCI papers.

PROFESSOR Rui-le PAN
Prof. Rui-le Pan Ph.D
        Prof. Pan Ruile is the vice director of Chemistry Department of the Research Center of Natural Product at the Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences (CAMS), Beijing, China. She has done her Bachelor Degree (Biology) from Sichuan University (Chengdu, China); Master Degree and Ph. D from Peking Union Medical College (Beijing, China).
        Prof. Pan was mainly engaged in the research of chemistry and standard of traditional Chinese
medicine, as well as drug discovery from Chinese herbal medicine. She has isolated more than 100 pure compounds from Cimicifuga foetida, Bupleurum chinensis, Polygala tenuifolia, Forsythia suspense, etc. using HSCCC and pre-HPLC and identified their structures on the basis of various spectral data. Quality standardization revision of Pharmacopoeia of Chinese People's Republic (2010) of Traditional Chinese Medicine Radix Bupleurae has established by her group. In recent years, Prof. Pan mainly focuses on active constituents in neurological disorders, including depression, anxiety, Alzheimer's disease (AD). She has Rewarded 5 times by Ministry of Health, Ministry of Science & Technology, State Administration of Traditional Chinese Medicine, and has published more than 50 scientific papers, including 8 SCI papers. Prof. Pan has been supervisor for Master Degree since 2005 and has produced 10 Master students.
        Research interests: chemistry and the quality standards of traditional Chinese medicine, product development from traditional Chinese medicine.

PROFESSOR Jian XUE

Prof. Jian Xue
        Have Master's Degree of Peking Union Medical College. Preside over or participate in 20 national items. Wined 4 ministry class award and published 50 papers, some of them appeared on JHS, J-Chrom-sci, Chemosphere.
        Have researched the effective components and quality criteria of some Traditional Chinese Medicine such as Glycyrrhizae Radix et Rhizoma、Bupleuri Radix、curcumae Radix、Zpaeoniae AlbRadix a、Ganoderma、Farfarae Flos、Carthami Flos、curcumae longae Rhizoma、Scutellariae

Radix、Astragali Radix、Ginseng Redix et Rhizome 、Panacis Quinquefolii Radix、Angelicae Sinensis Radix、Salviae Miltiorrhizae Radix et Rhizoma、Lonicerae Japonicae Flos、Rhei Radix et Rhizoma、Schizonepetae Herba、Pogostemonis Herba、Eupatorii Herba、Pini Lignum Nodi, and cooperate worked in new drug research ,bred medicinal materials breed and so on.
        The research on harmful substances (such as pesticide residues, heavy metals, solvent residues, toxin) in TCM include: Pesticide residue determine method and maximum residual limits(MRL),Contaminated status, Contamination database construct,Harmful substances remove, Rule of Chinese traditional medicine absorb harmful substances etc.
        Research interest:Analysis of effective components and quality criteria research of Traditional Chinese Medicine and research on harmful substances (such as pesticide residues, heavy metals, solvent residues, toxin) in TCM.
        TEL:010-62895076
        E-mail:jxue@implad.ac.cn;xuejian200@sina.com;xuejian5076@yahoo.com.cn

Dr. Lei Wang

Dr. Lei Wang
        Dr. Lei Wang obtained his B.S. in Traditional Chinese Medicinal Chemistry at Jilin Agricultural University in 2005. In the same year, he continued his study at Institute of Materia Medica, CAMS & PUMC and obtained his M.S. in Medicinal Chemistry in 2008 under the guidance of Prof. Ruoyun Chen. Then, he went abroad to National University of Singapore and obtained his Ph.D. in organic & medicinal chemistry in 2013 with Prof. Jian Wang. After that he started his German research stay supported by the Alexander von Humboldt

Foundation and had the honor of working with Prof. Dieter Enders at RWTH-Aachen as a postdoctoral associate in the field of organic chemistry. In 2017 he was awarded the related research funding from National Natural Science Foundation of China, the CAMS Innovation Fund for Medical Sciences and joined Department of Natural Medicinal Chemistry Research Center at IMPLAD, CAMS & PUMC as an associated professor. Currently, Dr. Wang focuses his research on asymmetric catalysis, medicinal chemistry and natural product chemistry. Dr. Wang has published more than 20 articles and awarded with one Natural Science Prize of Ministry of Education of China (Second Class), one Natural Science and Technology Prize of Beijing (First Class) and Alexander von Humboldt Scholars.
        Selected articles
        1. L. Wang, S. Li, M. Bl?mel, R. Puttreddy, A. Peuronen, K. Rissanen, D. Enders*, Angew. Chem. Int. Ed. 2017, 56, 8516-8521 (IF:11.994)
        2. L. Wang, S. Li, M. Bl?mel, R. Philipps, A. Wang, R. Puttreddy, K. Rissanen, D. Enders*, Angew. Chem. Int. Ed. 2016, 55, 11110-11114 (IF:11.994)
        3. L. Wang, S. Y. Peng, J. Wang*, Chem. –Eur. J. 2013, 19, 7555–7560 (Highlight in Chemistryviews) (IF:5.371)
        4. L. Wang, J. Y. Huang, S. Y. Peng, H. Liu, X. F. Jiang, J. Wang*, Angew. Chem. Int. Ed. 2013, 52, 1768-1772. (IF:11.994)
        5. L. Wang, S. Y. Peng, L. J. T. Danence, Y. J. Gao, J. Wang*, Chem. –Eur. J. 2012, 18, 6088-6093. (Highlight in SYNFACT) (IF:5.371)